Associate Director, Pathologist, Translational Science

Associate Director, Pathologist, Translational Science

Surface Oncology is working to advance next-generation approaches to cancer immunotherapy based on proprietary insights into novel immunotherapy targets and emerging areas of biology. We are seeking a creative and highly motivated experimental pathologist to be part of our growing company and member of the translational science team. The successful candidate will execute on pre-clinical and clinical translational activities essential for supporting the development of our immuno-oncology therapeutic portfolio towards the clinic.  The role will be highly collaborative, involving close cross-functional communication with colleagues throughout the organization. Qualified candidates should be independent, hard-working, and possess a proactive attitude who fit in well with the collaborative, rigorous and entrepreneurial spirit of our company culture.

Responsibilities:

  • Drive the development and interpretation of slide-based assays including histology, immunohistochemistry, in situ hybridization, and quantitative image analysis and provide leadership to the molecular pathology laboratory.
  • Provide translational scientific leadership and guidance for the biomarker strategy to one or more drug development programs within the therapeutic portfolio.
  • Oversight of translational science studies and activities designed to explore pharmacodynamics, mechanism of action, and predictive biomarkers including management of CRO vendor relationships with respect to clinical assay transfer and validation as well as clinical biomarker data analysis.
  • Authorship and/or review of translational science input into clinical documents including clinical trial protocols, informed consent forms, and clinical study reports as well as external scientific publications.
  • Maintain familiarity with current scientific literature, as well as novel technologies that may inform and facilitate translational science activities.
  • Prepare technical reports, summaries, protocols and quantitative analyses and interact collaboratively and communicate clearly with multidisciplinary teams.

Requirements/Qualifications

  • MD or DVM, with PhD preferred with 3+ years of academic, clinical, or industry anatomic pathology training/experience.
  • Demonstrated expertise in interpretation of histology, development of slide-based biomarker assays including immunohistochemistry and multiplex immunofluorescence methods, and experience in quantitative image analysis.
  • Research background and experience in cancer biology, immunology, and/or immuno-oncology is highly desirable.
  • Experience with assay transfer and validation, as well as management of Contract Research Organizations
  • Excellent interpersonal, organizational, communication, and problem-solving skills as well as the ability to work effectively as part of a multidisciplinary team.

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